Growth hormone deficiency and empty sella in DIDMOAD syndrome: an endocrine study.

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Growth hormone deficiency and empty sella in DIDMOAD syndrome: an endocrine study.

Two girls with DIDMOAD syndrome are presented. One also had severe megaloblastic-sideroblastic anaemia and the other several neurological manifestations. Both were short with defective growth hormone secretion. Computed tomography revealed empty sella in both girls; one had widespread atrophic cortical and cerebellar changes. High doses of thiamine improved the anaemia in the first case, increa...

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Prevalence of empty sella syndrome

Background: The empty sella syndrome (ESS) is a neurological or pathologic finding in which sella turcica is devoid of pituitary tissue and the subarachnoid space extends into sella turcica, which is either primary or secondary as well as partial and complete. The widespread use of CT scans and MRIs today has made the ESS a common finding in imaging. The aim of this study was to evaluate the pr...

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Multiple Pituitary Hormone Deficiency, Empty Sella and Ectopic Neurohypophysis in Turner Syndrome.

BACKGROUND Multiple pituitary hormone deficiency and Turner syndrome have overlapping features in peripubertal girls and is a diagnostic challenge. CASE CHARACTERISTICS 16-year-old girl having Turner phenotype undergoing evaluation for severe short stature and pubertal arrest. OBSERVATION 45,X karyotype, and multiple pituitary hormone deficiency with empty sella. INTERVENTION Levothyroxin...

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[The empty sella syndrome].

The empty sella syndrome (ESS) presents a varied clinical and radiographic picture. It may remain asymptomatic or may stimulate an intrasellar growth thereby causing diagnostic and therapeutic problems. An air encephalogram (AEG) is required for diagnosis. The purpose of this paper is to review the clinical and radiological features of the ESS and to discuss the pathogenetic mechanisms involved.

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Empty Sella Syndrome

Empty sel la refers to the radiological appearance of an enlarged or deformed sella turcica that is partially or completely filled with cerebrospinal fluid. In the earlier days, the radiographic appearance of an enlarged sella turcica was frequently equated with the presence of an intra or perisellar neoplasm. It was found, however, in some of these patients on pneumoencephalography, that the e...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1995

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.73.3.251